Erythropoietin therapy is one of the greatest inventions in Nephrology and it changed the way we treat anemic patients, which we were only dependent on blood transfusions in the past. Erythropoietin therapy is the easiest way to treat anemia in CKD
Author: Hemanth Prakash
Erythropoietin Therapy
Erythropoietin therapy is one of the greatest inventions in Nephrology and it changed the way we treat anemic patients, which we were only dependent on blood transfusions in the past. Erythropoietin is a 165 amino acid secreted glycoprotein. Recombinant erythropoietin is available in two forms α-epoetin and β-epoetin and Darbepoetin is a longer acting erythropoietin with the half-life approximately three folds longer than recombinant erythropoietin. 1µg darbepoetin is equal to 200 IU OF erythropoietin.This has been achieved by adding two extra N – linked carbohydrate side – chains to the erythropoietin molecule. As a result, darbepoetin requires less frequent dosage, usually once a week or once in every two weeks and sometimes only once a month in stable hemodialysis patients.
Management of Anemia in Chronic Kidney Disease (CKD)
There are two important reasons to correct anemia in renal failure patients. One is to improve or reverse the symptoms associated with renal anemia, and the second is to seize or reverse the deleterious effect of long-standing anemia on the heart and other organs which lead to improved cardiovascular morbidity and mortality in dialysis patients.
Development Of Anemia In Dialysis Patients
Anemia is one of the major Hematological complications in Chronic Kidney Disease (CKD). As renal function declines, there is a progressive worsening of anemia, which becomes clear once serum creatinine rises above 300 µmol/L or GFR falls below 30 ml/min/1.73m² and its major cause is the loss of cells in the kidney responsible for the synthesis and secretion of erythropoietin.
Anemia In Dialysis Patients
Anemia is one of the major Hematological complications in Chronic Kidney Disease (CKD). Although anemia in CKD is multifactorial by far the main cause of anemia is due to inadequate production of hormone Erythropoietin by the diseased kidneys.
Renal Dietitians! What Do You Do?
Every hospital has a dietitian, and renal dietitians are the one who has expert knowledge in renal disease and its stages and management and knows to control rapid failure of your kidney through diet modifications. Diet plays a huge role in dialysis patients and renal dietitians guide the renal failure and dialysis patients to a right path leading to a better quality of life.
10 Rights of Dialysis Patients
Be treated at the facility of your choice and with consideration and respect and in full recognition of your individual and personal needs including the right to privacy in treatment
7 Things Dialysis Technician Does To Keep Patients Safe During Dialysis
Dialysis technicians are also known as Patient care technicians are the one who looks after dialysis patients on dialysis and sticks to their protocols to give best of treatment and make sure that you have a comfortable and complication free dialysis. Dialysis technicians monitor your vitals until the dialysis treatment finishes and make sure that you had your post dialysis medications and send you home happily. Dialysis Technicians are the one who is responsible and strive hard to improve your quality of life.
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